Symptomology, Outcomes and Risk Factors of Acute Coronary Syndrome Presentations without Cardiac Chest Pain: A Scoping Review

Author:

Perona Meriem1ORCID,Cooklin Amanda2ORCID,Thorpe Christopher3ORCID,O’Meara Peter4ORCID,Rahman Muhammad Aziz5ORCID

Affiliation:

1. Judith Lumley Centre, School of Nursing and Midwifery, La Trobe University, Victoria, Australia; Ambulance Victoria, Melbourne, Australia

2. Judith Lumley Centre, School of Nursing and Midwifery, La Trobe University, Victoria, Australia

3. Ambulance Victoria, Melbourne, Australia

4. Department of Paramedicine, Monash University, Melbourne, Australia

5. Institute of Health and Wellbeing, Federation University Australia, Melbourne, Australia; Faculty of Public Health, Universitas Airlangga, Surabaya, Indonesia; Department of Non-Communicable Diseases, Bangladesh University of Health Sciences, Dhaka, Bangladesh

Abstract

For patients experiencing acute coronary syndrome, early symptom recognition is paramount; this is challenging without chest pain presentation. The aims of this scoping review were to collate definitions, proportions, symptoms, risk factors and outcomes for presentations without cardiac chest pain. Full-text peer reviewed articles covering acute coronary syndrome symptoms without cardiac chest pain were included. MEDLINE, CINAHL, Scopus and Embase were systematically searched from 2000 to April 2023 with adult and English limiters; 41 articles were selected from 2,954. Dyspnoea was the most reported (n=39) and most prevalent symptom (11.6–72%). Neurological symptoms, fatigue/weakness, nausea/vomiting, atypical chest pain and diaphoresis were also common. Advancing age appeared independently associated with presentations without cardiac chest pain; however, findings were mixed regarding other risk factors (sex and diabetes). Patients without cardiac chest pain had worse outcomes: increased mortality, morbidity, greater prehospital and intervention delays and suboptimal use of guideline driven care. There is a need for structured data collection, analysis and interpretation.

Publisher

Radcliffe Media Media Ltd

Reference78 articles.

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