1. Department of Laboratory Medicine, Institute of Biomedicine, University of Gothenburg , SE-413 45 Gothenburg , Sweden
2. Department of Health and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg , Gothenburg , Sweden
3. BHF Centre for Cardiovascular Science, University of Edinburgh , Edinburgh , UK
4. Usher Institute, University of Edinburgh , Edinburgh , UK
5. Cardiovascular research Institute Basel (CRIB) and Department of Cardiology, University Hospital Basel, University of Basel , Switzerland