Meta-analysis of the Relationship Between Dose and Benefit in Phase I Targeted Agent Trials
Author:
Publisher
Oxford University Press (OUP)
Subject
Cancer Research,Oncology
Link
http://academic.oup.com/jnci/article-pdf/104/24/1860/7674738/djs439.pdf
Reference17 articles.
1. Nontoxicity Endpoints in Phase I Trial Designs for Targeted, Non-Cytotoxic Agents
2. Phase I Trial Design for Solid Tumor Studies of Targeted, Non-Cytotoxic Agents: Theory and Practice
3. Response rates, duration of response, and dose response effects in phase I studies of antineoplastics
4. Clinical benefit in Phase-I trials of novel molecularly targeted agents: does dose matter?
5. Dose Selection in Phase I Studies: Why We Should Always Go for the Top
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