Phase II Trial of Trametinib and Panitumumab in RAS/RAF Wild Type Metastatic Colorectal Cancer
Author:
Funder
Conquer Cancer Foundation
Canadian Cancer Society Research Institute
Canadian Cancer Society
Publisher
Elsevier BV
Subject
Gastroenterology,Oncology
Reference32 articles.
1. Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: updated analysis of overall survival according to tumor KRAS and BRAF mutation status;Van Cutsem;J Clin Oncol,2011
2. Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer;Douillard;N Engl J Med,2013
3. Mutations of the BRAF gene in human cancer;Davies;Nature,2002
4. BRAF mutation is frequently present in sporadic colorectal cancer with methylated hMLH1, but not in hereditary nonpolyposis colorectal cancer;Deng;Clin Cancer Res,2004
5. Mutations of KRAS and BRAF in primary and matched metastatic sites of colorectal cancer;Artale;J Clin Oncol,2008
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