Phenolic Substances in Foods and Anticarcinogenic Properties: A Public Health Perspective

Author:

Laganà Pasqualina1,Coniglio Maria Anna2,Fiorino Marco3,Delgado Amélia Martins4ORCID,Chammen Nadia5,Issaoui Manel6,Gambuzza Maria E7,Iommi Candela8,Soraci Luca9,Haddad Moawiya A10,Delia Santi1

Affiliation:

1. Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy

2. Department “G.F. Ingrassia”, University of Catania, Catania, Italy

3. Studio Tecnico Fiorino, Siracusa, Italy

4. MeditBio-Centre for Mediterranean Bioresources and Food, University of Algarve, Faro, Portugal

5. Laboratoire d’Ecologie et de Technologie Microbienne, Institut National des Sciences Appliquées et de Technologie (INSAT), University of Carthage, Tunis, Tunisia

6. Lab –NAFS Nutrition – Functional Food & Vascular Health, Faculty of Medicine, University of Monastir, Monastir, Tunisia

7. Ministry of Health, Territorial Office of Messina, Messina, Italy

8. Food Safety Consultant, Via Aselli 14, Milan, Italy

9. Clinical and Experimental Medicine Department, University of Messina, Messina, Italy

10. Department of Nutrition and Food Processing, Faculty of Agricultural Technology, Al-Balqa Applied University, Al-Salt, Jordan

Abstract

Abstract The interest in polyphenols from vegetable sources has been progressively increased because of the demonstrated correlation between their abundance in certain foods or food preparations of traditional importance and heritage, and the answer of anti-inflammatory strategies in hospitalized patients in the presence of polypehnol-rich foods (as a complementary therapy). Consequently, research involving the accessory role of polyphenols as anti-tumoral aids have been carried out with the aim of finding new additional strategies. The purpose of this paper to evaluate the role of phenolic compounds in foods with reference to health effects for human beings. The importance of these molecules has been evaluated by the health and safety perspectives in terms of: fight to cardiovascular diseases; prevention of chronic-degenerative disorders; general antioxidant properties; and anticarcinogenic features. Moreover, the role of polyphenols-rich foods as anticancer agents has been discussed with relation to two distinct “action plans” on the public hygiene level: the promotion of human health on the one side (for non-hospitalized and normal subjects), and reliable contrasting strategies in cancer patients.

Publisher

Oxford University Press (OUP)

Subject

Pharmacology,Agronomy and Crop Science,Environmental Chemistry,Food Science,Analytical Chemistry

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