This article provides an in-depth look at all aspects of the climate of the Sahel, including the pervasive dust in the Sahelian atmosphere. Emphasis is on two aspects: West African monsoon and the region’s rainfall regime. This includes an overview of the prevailing atmospheric circulation at the surface and aloft and the relationship between this and the rainfall regime. Aspects of the rainfall regime that are considered include its unique characteristics, its changes over time, the storm systems that produce rainfall, and factors governing its variability on interannual and decadal time scales. Variability is examined on three time scales: millennial (as seen is the paleo records of the last 20,000 years), multi-decadal (as seen over the last few centuries as seen from proxy data and, more recently, in observations), and interannual to decadal (quantified by observations from the late 19th century and onward). A unique feature of Sahel climate is that is rainfall regime is perhaps the most sensitive in the world and this sensitivity is apparent on all of these time scales.