Acquisition of cross-azole tolerance and aneuploidy in Candida albicans strains evolved to posaconazole
Author:
Affiliation:
1. Department of Microbiology, The University of Manitoba , Winnipeg, MB R3T 2N2, Canada
2. Department of Statistics, The University of Manitoba , Winnipeg, MB R3T 2N2, Canada
Abstract
Funder
NSERC Discovery Grant
University of Manitoba and a University of Manitoba University Research Grants Program
University of Manitoba, Faculty of Science
NSERC Undergraduate Student Research Awards
EvoFunPath
Publisher
Oxford University Press (OUP)
Subject
Genetics (clinical),Genetics,Molecular Biology
Link
https://academic.oup.com/g3journal/advance-article-pdf/doi/10.1093/g3journal/jkac156/45254873/jkac156.pdf
Reference87 articles.
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2. YMAP: a pipeline for visualization of copy number variation and loss of heterozygosity in eukaryotic pathogens;Abbey;Genome Med,2014
3. A chromosome 4 trisomy contributes to increased fluconazole resistance in a clinical isolate of Candida albicans;Anderson;Microbiology,2017
4. EUCAST technical note on posaconazole;Arendrup;Clin Microbiol Infect,2011
5. Formation of azole-resistant Candida albicans by mutation of sterol 14-demethylase P450;Asai;Antimicrob Agents Chemother,1999
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