Novel Point Mutations in cyp51A and cyp51B Genes Associated with Itraconazole and Posaconazole Resistance in Aspergillus clavatus Isolates-Reference-Cited by-同舟云学术

Novel Point Mutations in cyp51A and cyp51B Genes Associated with Itraconazole and Posaconazole Resistance in Aspergillus clavatus Isolates

Published:2019-06 Issue:5 Volume:25 Page:652-662
ISSN:1076-6294
Container-title:Microbial Drug Resistance
language:en
Short-container-title:Microbial Drug Resistance

Author:

Abastabar Mahdi¹²,Hosseini Tahereh³,Valadan Reza⁴⁵,Lagzian Milad⁶,Haghani Iman¹²,Aslani Narges⁷,Badali Hamid¹²,Nouripour-Sisakht Sadegh⁸,Nazeri Mehdi⁹,Gholami Sara²,Vakili Mahshid³,Bowyer Paul¹⁰¹¹,Shokohi Tahereh¹²,Hedayati Mohammad T.¹²

Affiliation:

1. Invasive Fungi Research Center (IFRC), School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

2. Department of Medical Mycology, Mazandaran University of Medical Sciences, Sari, Iran.

3. Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran.

4. Department of Immunology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

5. Molecular and Cell Biology Research Center, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

6. Department of Biology, Faculty of Science, University of Sistan and Baluchestan, Zahedan, Iran.

7. Infectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

8. Medicinal Plants Research Center, Yasuj University of Medical Sciences, Yasuj, Iran.

9. Medical Parasitology and Mycology Department, Kashan University of Medical Sciences, Kashan, Iran.

10. Manchester Fungal Infection Group, Division of Infection Immunity and Respiratory Medicine, School of Biological Sciences, University of Manchester, Manchester, United Kingdom.

11. Manchester Academic Health Science Centre, University NHS Foundation Trust (Wythenshawe), Manchester, United Kingdom.

Publisher

Mary Ann Liebert Inc

Subject

Microbiology (medical),Pharmacology,Immunology,Microbiology

Link

https://www.liebertpub.com/doi/pdf/10.1089/mdr.2018.0300

Reference38 articles.

1. Azole Resistance in Aspergillus fumigatus Isolates from the ARTEMIS Global Surveillance Study Is Primarily Due to the TR/L98H Mutation in thecyp51AGene

2. Development of monoclonal antibody-based galactomannoprotein antigen-capture ELISAs to detect Aspergillus fumigatus infection in the invasive aspergillosis rabbit models

3. Invasive pulmonary aspergillosis: current diagnostic methodologies and a new molecular approach

4. Aspergillus flavus: human pathogen, allergen and mycotoxin producer

5. Extrinsic allergic alveolitis in Scottish maltworkers.

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