Quantitative proteomics identifies proteins that resist translational repression and become dysregulated in ALS-FUS

Author:

Baron Desiree M1,Matheny Tyler2,Lin Yen-Chen1,Leszyk John D34,Kenna Kevin15,Gall Katherine V1,Santos David P67,Tischbein Maeve1,Funes Salome1,Hayward Lawrence J1,Kiskinis Evangelos67,Landers John E1,Parker Roy28,Shaffer Scott A34,Bosco Daryl A13

Affiliation:

1. Department of Neurology, University of Massachusetts Medical School, Worcester, MA, USA

2. Department of Chemistry and Biochemistry, University of Colorado, Boulder, CO, USA

3. Department of Biochemistry and Molecular Pharmacology, Worcester, MA, USA

4. Mass Spectrometry Facility, University of Massachusetts Medical School, Shrewsbury, MA, USA

5. Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands

6. The Ken & Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

7. Department of Physiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

8. Howard Hughes Medical Institute, Chevy Chase, MD, USA

Funder

National Institutes of Health

ALS Therapy Alliance

ALS Association

Les Turner ALS Foundation

Muscular Dystrophy Association

NIA

Publisher

Oxford University Press (OUP)

Subject

Genetics (clinical),Genetics,Molecular Biology,General Medicine

Reference88 articles.

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2. Stress-specific differences in assembly and composition of stress granules and related foci;Aulas;J. Cell Sci.,2017

3. Principles and properties of stress granules;Protter;Trends Cell Biol.,2016

4. Unravelling the ultrastructure of stress granules and associated P-bodies in human cells;Souquere;J. Cell Sci.,2009

5. The molecular language of membraneless organelles;Gomes;J. Biol. Chem.,2018

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