Proteins Involved in Endocytosis Are Upregulated by Ageing in the Normal Human Brain: Implications for the Development of Alzheimer’s Disease

Author:

Alsaqati Mouhamed12,Thomas Rhian S13,Kidd Emma J1ORCID

Affiliation:

1. School of Pharmacy and Pharmaceutical Sciences, Cardiff University, UK

2. Neuroscience and Mental Health Research Institute, Cardiff University, UK

3. Department of Applied Sciences, Faculty of Health and Applied Sciences, University of the West of England, Bristol, UK

Funder

Bristol Research into Alzheimer’s and Care of Elderly (BRACE)

Publisher

Oxford University Press (OUP)

Subject

Geriatrics and Gerontology,Aging

Reference54 articles.

1. 2016 Alzheimer’s disease facts and figures;Alzheimer’s Association;Alzheimer’s & Dementia,2016

2. Strategies for disease modification in Alzheimer’s disease;Citron;Nat Rev Neurosci,2004

3. Inhibition and modulation of gamma-secretase for Alzheimer’s disease;Wolfe;Neurotherapeutics,2008

4. Evidence that production and release of amyloid beta-protein involves the endocytic pathway;Koo;J Biol Chem,1994

5. The alpha secretase ADAM10: a metalloprotease with multiple functions in the brain;Saftig;Prog Neurobiol,2015

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