Feasibility of Remote Administration of the Uniform Data Set-Version 3 for Assessment of Older Adults With Mild Cognitive Impairment and Alzheimer’s Disease

Author:

Sachs Bonnie C123ORCID,Latham Lauren A23,Bateman James R1,Cleveland Mary Jo23,Espeland Mark A234,Fischer Eric23,Gaussoin Sarah A4,Leng Iris4,Rapp Stephen R5,Rogers Samantha23,Shappell Heather M4,Williams Benjamin J123,Yang Mia23,Craft Suzanne23

Affiliation:

1. Department of Neurology, Wake Forest School of Medicine , Winston-Salem, NC , USA

2. Section on Gerontology and Geriatric Medicine , Department of Internal Medicine, , Winston-Salem, NC , USA

3. Wake Forest School of Medicine , Department of Internal Medicine, , Winston-Salem, NC , USA

4. Department of Biostatistics and Data Science, Wake Forest School of Medicine , Winston-Salem, NC , USA

5. Department of Psychiatry and Behavioral Medicine, Wake Forest School of Medicine , Winston-Salem, NC , USA

Abstract

Abstract Objective Assess the feasibility and concurrent validity of a modified Uniform Data Set version 3 (UDSv3) for remote administration for individuals with normal cognition (NC), mild cognitive impairment (MCI), and early dementia. Method Participants (N = 93) (age: 72.8 [8.9] years; education: 15.6 [2.5] years; 72% female; 84% White) were enrolled from the Wake Forest ADRC. Portions of the UDSv3 cognitive battery, plus the Rey Auditory Verbal Learning Test, were completed by telephone or video within ~6 months of participant’s in-person visit. Adaptations for phone administration (e.g., Oral Trails for Trail Making Test [TMT] and Blind Montreal Cognitive Assessment [MoCA] for MoCA) were made. Participants reported on the pleasantness, difficulty, and preference for each modality. Staff provided validity ratings for assessments. Participants’ remote data were adjudicated by cognitive experts blinded to the in person-diagnosis (NC [N = 44], MCI [N = 35], Dementia [N = 11], or other [N = 3]). Results Remote assessments were rated as pleasant as in-person assessments by 74% of participants and equally difficult by 75%. Staff validity rating (video = 92%; phone = 87.5%) was good. Concordance between remote/in-person scores was generally moderate to good (r = .3 −.8; p < .05) except for TMT-A/OTMT-A (r = .3; p > .05). Agreement between remote/in-person adjudicated cognitive status was good (k = .61–.64). Conclusions We found preliminary evidence that older adults, including those with cognitive impairment, can be assessed remotely using a modified UDSv3 research battery. Adjudication of cognitive status that relies on remotely collected data is comparable to classifications using in-person assessments.

Funder

National Institute of Health

Publisher

Oxford University Press (OUP)

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