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Enhancers: bridging the gap between gene control and human disease

  • Published:2018-05-02 Issue:R2 Volume:27 Page:R219-R227
  • ISSN:0964-6906
  • Container-title:Human Molecular Genetics
  • language:en
  • Short-container-title:

Author:

Karnuta Jaret M12,Scacheri Peter C1

Affiliation:

1. Department of Genetics and Genome Sciences, Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH, USA

2. Cleveland Clinic Lerner College of Medicine, Cleveland, OH, USA

Funder

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Genetics(clinical),Genetics,Molecular Biology,General Medicine

Reference97 articles.

1. An integrated encyclopedia of DNA elements in the human genome;ENCODE Project Consortium;Nature,2012

2. Integrative analysis of 111 reference human epigenomes;Roadmap Epigenomics Consortium;Nature,2015

3. The human noncoding genome defined by genetic diversity;di Iulio;Nat. Genet,2018

4. Histone modifications at human enhancers reflect global cell-type-specific gene expression;Heintzman;Nature,2009

5. Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome;Heintzman;Nat. Genet,2007
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