Open-source, partially 3D-printed, high-pressure (50-bar) liquid-nitrogen-cooled parahydrogen generator
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Published:2021-02-18
Issue:1
Volume:2
Page:49-62
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ISSN:2699-0016
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Container-title:Magnetic Resonance
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language:en
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Short-container-title:Magn. Reson.
Author:
Ellermann FrowinORCID, Pravdivtsev AndreyORCID, Hövener Jan-BerndORCID
Abstract
Abstract. The signal of magnetic resonance imaging (MRI) can be
enhanced by several orders of magnitude using hyperpolarization. In
comparison to a broadly used dynamic nuclear polarization (DNP) technique that is already used in clinical trials, the parahydrogen (pH2)-based hyperpolarization approaches are less cost-intensive, are scalable, and offer high throughput. However, a pH2 generator is necessary. Available
commercial pH2 generators are relatively expensive
(EUR 10 000–150 000). To facilitate the spread of pH2-based hyperpolarization studies, here we provide the blueprints and 3D models as open-source for a low-cost (EUR <3000) 50-bar liquid-nitrogen-cooled pH2 generator.
Publisher
Copernicus GmbH
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