Tương quan giữa thang điểm MDS-UPDRS phần II và thang đo Schwab và England trong đánh giá hoạt động sống hàng ngày ở bệnh nhân bệnh Parkinson mới chẩn đoán

Abstract

Background: Activities of daily living scales are often used to assess functional impairment in Parkinson’s patients, of which the Schwab & England scale is one of the most commonly used scales, while the MDS-UPDRS part II has been recently used.Objectives: To determine the correlation between two scales assessing activities of daily living in patients with Parkinson’s disease: the MDS - UPDRS part II and the Schwab & England scale.Methods: This is a cross-sectional study conducted on patients with newly diagnosed Parkinson’s disease according to the criteria of the 2015 International Parkinson and Movement Disorders Society at the Parkinson’s and Movement Disorders Clinic, University Medical Center HCMC from November 2022 to June 2023. Demographic data, clinical characteristics, MDS-UPDRS, and Schwab & England scale were collected from participating subjects. Data were analysed by using Rstudio-2023.06.01 and Epidata 4.6.0.6 software.Results: A total of 61 patients with Parkinson’s disease met the criteria. The activities of daily living ’s score based on the Schwab & England scale was 78.53 ± 10.93, ranging from 60% to 100%. All patients with no impact on activities of daily living and moderate impact based on the MDS - UPDRS part II scale had Schwab & England scores > 80% and < 80%, respectively. The MDS-UPDRS part II scale has a strong, negative correlation with the Schwab & England activities of daily living scale (r = -0.74, p < 0.001).Conclusions: The MDS-UPDRS part II scale has a strong, negative correlation with the Schwab & England activities of daily living scale.