Immunomodulating Effects of the Peptides Derived from Whey Protein

Abstract

Immunomodulating properties of the peptides derived from whey protein isolates (WPI) were evaluated by measuring their effects on the proliferation of mice spleen lymphocytes and the phagocytosis of mice peritoneal macrophages in vitro. The results showed that the peptides derived-from WPI significantly increased the mice lymphocytes proliferation and the mice peritoneal macrophages phagocytosis at a concentration of 200 mgmL-1. Therefore, the results demonstrate that WPI contain some immunomodulating peptides, which can be released by hydrolyzed.