Optimization of Polydimethylsiloxane Synthesized Parameters as Vitreous Humour Substitutes

Author:

Setiadji Soni1,Fitrilawati 1,Fauza Anna Niska1,Ardi Atikah1,Novianti Ressa Muhrifah1,Syakir Norman1,Waslaluddin 1,Rahayu Iman1,Kartasasmita Arief Sjamsulaksan2,Risdiana 1

Affiliation:

1. Universitas Padjadjaran

2. Padjadjaran University

Abstract

Polydimethylsiloxane (PDMS) with two type viscosity that commonly used as vitreous humour substitutes in vitreoretinal surgery has been successfully synthesized by ring-opening polymerization. Optimization of synthesized parameters such as ratio of monomer and chain terminator, the amount of initiator, mixing temperature and reaction time was carried out to obtain PDMS materials having similar properties with commercial product. PDMS with viscosity of 1.17 Pas that very close to viscosity of commercial PDMS of 1.08 Pas, was successfully synthesized with a ratio of 26:10 monomer and terminator chain, 0.58 M of initiator KOH, 170 oC of mixing temperature and 35 minutes of reaction time. By changing reaction time to 40 minutes, PDMS was successfully synthesized with viscosity of 3.42 that similar to that of commercial one.

Publisher

Trans Tech Publications, Ltd.

Subject

Mechanical Engineering,Mechanics of Materials,Condensed Matter Physics,General Materials Science

Reference15 articles.

1. A.K. Khurana, Comprehensive Ophthalmology, fourth ed., New Age International (P) Ltd, India, 2007, pp.247-276.

2. M. Azarmina, M. Soheilian, H. Azarmina, B. Hosseini, Electroretinogram Changes following Silicone Oil Removal., J. Ophthalmic Vis Res. 6(2) (2011) 109-113.

3. B. Lee, M. Litt, G. Buchsbaum, Rheology of the vitreous body. Part I: Viscoelasticity of human vitreous., Biorheology 29(5-6) (1992) 521-533.

4. R. Snell, Head and neck, In: Clinical anatomy for medical surgery, Little, Brown and Co., NY, USA, 1995, pp.723-725.

5. K.E. Swindle, N. Ravi, Recent advances in polymeric vitreous substitutes, J. Exp Rev Ophthalmology 2 (2007) 255-265.

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