Anti-Fatigue Activity of Pecan Oil in Mice

Abstract

In the present study, we investigated the anti-fatigue activity in male Kunming mice with pecan oil using a forced swimming test. Mice were divided into four groups (three pecan oil administered groups and a control group). The control group was gavaged with distilled water and pecan oil administered groups were gavaged with pecan oil (10, 20 and 30mg/10g body weight /d). After four weeks, a forced swimming test was performed and the biochemical parameters related to fatigue were examined. The results suggested that pecan oil could extend the swimming time to exhaustion of the mice, as well as increase the tissue glycogen contents, while decreasing the blood lactate and serum urea nitrogen contents. This indicated that pecan oil had anti-fatigue activity and could elevate the exercise tolerance.