Mechanical Property Evaluation of PLA/Soybean Oil Epoxidized Acrylate Three-Dimensional Scaffold in Bone Tissue Engineering

Abstract

Recently investigated photocurable, biocompatible plant resin on tissue engineering to provide the scaffold with structural support and mechanical properties. A novel method had been used here to build our scaffold by combined the traditional three-dimensional fused deposition modeling (FDM) printing and injected the structural scaffold after fabrication with plant-based resin. The materials used are polymers a synthesized one polylactic acid and soybean oil epoxidized acrylate. The addition of soybean plant-based resin improves the adhesion and proliferation of the PLA scaffold while also providing structural support to the fabricated scaffold. The purpose of the study made optimization of printing parameters and compared different printing scaffolds to select the perfect one with preferred mechanical properties. Two designs are built (cubic design and cylinder design) to make a comparison of mechanical properties between the two designs. The novel method was used through injected soybean oil resin into the PLA scaffold by avoiding any heat and temperature rise of the resin. In the traditional method, the resin is printed using an SLA printer which exposed the resin to heating before printing, this will affect the properties of the final model in our technique temperature will eliminate by direct inject the plant-based resin into the PLA scaffold and then photocuring with ultraviolet curing device for 30 min at 405nm. Finally, the results demonstrate that after injecting PLA scaffold with soybean oil resin, the mechanical properties of the scaffold improve; additionally, the results show that the cylindrical design has more promising mechanical properties than the cubic design.