Evaluation of a design for a three‐dimensional‐printed artificial bone structure

Abstract

AbstractIn this work, artificial bones composed of hydroxyapatite (HA)/polyacrylonitrile (PAN) and polylactic acid (PLA) were prepared as a potential replacement for natural bone. The cylindrical specimens included an auxetic system with artificial osteons. HA/PAN and PLA were used to fabricate composite filaments by fused deposition modeling three‐dimensional (3D) printing, and the obtained filaments were applied to produce reentrant artificial bone materials. Scanning electron microscopy was used to analyze the scaffold morphology and functional groups. Energy‐dispersive X‐ray spectroscopy was used for elemental analysis. The compressive properties of the samples were studied to determine the optimal scaffolding prototype. Compressive tests were also performed to assess the behavior of the cellular structure from a mechanical perspective. Finally, ANOVA and residual plots were used to investigate the contributions of the design elements, predict the y‐coordination of the stress values, and evaluate the printing orientation. The results indicated that the auxetic cells influenced the bone macrostructure, which displayed different stiffness characteristics in one working direction. Polymeric solution biomaterials based on HA/PAN and PLA biopolymers have enormous potential as high‐performance liquid synthetic organic polymers for light‐supported extrusion‐based 3D printing. PLA/HA scaffoldings with outstanding medical conversion capability may be used as biomaterial composites for bone deficiency restoration.Highlights Composite filaments for FDM 3D printing were used to manufacture reentrant artificial bone. A replacement method was utilized to determine the porosity of the scaffolds. Mechanically, this cellular structure was evaluated using compressive studies. SEM was used to assess scaffold morphology, functional categories, and elements. Create biodegradable constructions using as little material as possible.