Author:
Kadentsev V.I.,Chizhov A.O.,Chizhov O.S.,Krupinova O.N.,Rzheznikov V.M.,Golubovskaya L.E.
Abstract
The fragmentation of [M + Na]+ ions produced from steroid 11β-nitrates during electrospray ionization (ESI) was studied by using the ion trap MS/MS technique. The [M + Na]+ ions eliminate NO2 and HNO3 for epimers bearing 9β and 9α substituents, respectively. As the main fragmentation pathways are determined mainly by the configuration at C-9 and alternative fragmentation hardly occur, this offers the possibility for deteermining the configurationof the estrane 11β nitrate series at the chiral C-9 center using ESI mass spectrometry.
Subject
Spectroscopy,Atomic and Molecular Physics, and Optics,General Medicine
Cited by
6 articles.
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