Can Elimination Diets be Promising for Neurodegenerative Diseade?

Abstract

Medical nutrition interventions are an integral part of the multidisciplinary management of different medical disorders. Food allergies are becoming increasingly common and better recognized. "Elimination diets" are a dietary approach based on the elimination of certain allergenic foods or, in cases where it is not known which foods are allergenic, the elimination of potentially allergenic foods from the diet. Maintaining elimination diets can be highly effective in reducing the symptoms of food allergies. The gut microbiota has important effects on the structure and function of the enteric and central nervous system, including human behavior and brain regulation. The gut-microbiome-brain axis is now recognized as an important part in the regulation of systemic metabolism and homeostasis. Nutrients can cause inflammation by affecting the neural pathways through the vasoconstrictor or vasodilator effects of some of the substances they contain. Therefore, maintaining the gut microbiota and prioritizing anti-inflammatory nutrients and eliminating certain nutrients that are predicted to cause damage to the body are important in the nutritional treatment of neurodegenerative diseases. Elimination diets, which are mainly used for food allergies, have been suggested to be effective in the treatment of neurodegenerative diseases. For this reason, it has become the focus of more intensive research in neurological and psychiatric pathologies, especially as it may alleviate emotional eating disorders such as anxiety and depression. The evidence in this review summarizes balanced and high-quality elimination diets as a promising medical nutrition therapy to support immune and neuronal homeostasis.