Affiliation:
1. Memorial Sloan Kettering Cancer Center (MSKCC); Parker Institute for Cancer Immunotherapy; MSKCC Center for Cell Engineering; Weill Cornell Medical and Graduate Schools, New York, NY
Abstract
In this issue of JEM, Chheda et al. (https://doi.org/10.1084/jem.20171046) report that a conserved hotspot mutation associated with an aggressive form of brain cancer generates an immunogenic T cell epitope restricted by a common HLA subtype, thereby creating a “public” neoantigen.
Publisher
Rockefeller University Press
Subject
Immunology,Immunology and Allergy
Cited by
46 articles.
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