Affiliation:
1. From the Irvington House Institute and the Departments of Medicine and Pathology, New York University School of Medicine, New York 10016
Abstract
Thymocytes, bone marrow cells, and their derived T and B cell populations were examined for the presence of Ig by the cell surface radioiodination technique. Both IgM and IgG were identified on bone marrow cells. Thymocytes and T cells had no detectable cell surface Ig. Radiolabeling of mixtures of B cells and thymocytes suggest that the method may detect as little as 250 molecules of Ig per cell. Based on these findings, we suggest that the T cell receptor for antigen is not a conventional tetrameric Ig.
Publisher
Rockefeller University Press
Subject
Immunology,Immunology and Allergy
Cited by
137 articles.
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