TLR8: No gain, no pain-Reference-Cited by-同舟云学术

TLR8: No gain, no pain

Published:2018-11-19 Issue:12 Volume:215 Page:2964-2966
ISSN:0022-1007
Container-title:Journal of Experimental Medicine
language:en
Short-container-title:

Author:

Barrat Franck J.¹²^ORCID

Affiliation:

1. Autoimmunity and Inflammation Program, HSS Research Institute, Hospital for Special Surgery, New York, NY

2. Department of Microbiology and Immunology, Weill Cornell Medical College of Cornell University, New York, NY

Abstract

TLRs have been well characterized in the context of immunity, although TLR8 is understudied due to its controversial function in mice. In this issue of JEM, the new work by Zhang et al. (https://doi.org/10.1084/jem.20180800) demonstrates that TLR8 activated by miR-21 controls neuropathic pain using a non-MyD88–dependent pathway.

Publisher

Rockefeller University Press

Subject

Immunology,Immunology and Allergy

Link

http://rupress.org/jem/article-pdf/215/12/2964/1169941/jem_20181899.pdf

Reference12 articles.

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