Topical Mupirocin for Eradication of MRSA Colonization With Mupirocin-Resistant Strains

Abstract

AbstractTopical mupirocin was able to interrupt colonization of 52% and 68% of methicillin-resistantStaphylococcus aureus(MRSA)-colonized patients carrying mupirocin-resistant and -sensitive strains, respectively, including 44.4% and 85.7% of those colonized only in the nares. Although a trend to decreased effectiveness was seen for clearing mupirocin-resistant MRSA this agent can decolonize many patients with resistant strains.