A Greener, Versatile and Convenient Approach for Catalyst Free Conversion of Pyrazole Aldehydes into Carbonitriles

Author:

Jayanthi Selvaraj1ORCID,Pramesh Manickam1ORCID,Monisha Periyasamy1ORCID,Vetriselvan Moorthy1ORCID,Venkatachalam Ragunathan1

Affiliation:

1. PG and Research Department of Chemistry, A.V.V.M. Sri Pushpam College (Affiliated to Bharathidasan University, Tiruchirappalli), Poondi-613503, India

Abstract

A new, efficient and catalyst-free synthetic strategy was developed for ten carbonitriles by the combination of pyrazole aldehydes and hydroxylamine hydrochloride in the presence of green solvent-glycerol. All the synthesized carbonitriles were confirmed from by 1H, 13C NMR and high resolution mass spectroscopies. The proposed synthetic process was simple, effective with high product yields and environmentally benign with mild reaction conditions.

Publisher

Asian Journal of Chemistry

Subject

General Chemistry

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