Design, Synthesis, Characterization and Biological Activities of Recent Isatin Derivatives with Proven Pharmacophoric Moiety-Reference-Cited by-同舟云学术

Design, Synthesis, Characterization and Biological Activities of Recent Isatin Derivatives with Proven Pharmacophoric Moiety

Published:2020 Issue:11 Volume:32 Page:2731-2738
ISSN:0975-427X
Container-title:Asian Journal of Chemistry
language:en
Short-container-title:Asian J. Chem.

Author:

Bhatnagar Ruchi¹^ORCID,Pandey Jaya¹^ORCID,Panhekar Deepa²^ORCID

Affiliation:

1. Department of Chemistry, Amity University, Lucknow Campus, Lucknow-226028, India

2. Department of Chemistry, Dr. Ambedkar College, Deekshaboomi, Nagpur-440008, India

Abstract

Isatin derivatives, alkylated with proven pharmacophoric moiety were synthesized for various biodynamic activities. To enhance some biodynamic properties like antibacterial and antifungal, imine formation with various compounds at C3 was analyzed. The isatin derivatives were characterized and examined for various biodynamic activities on bacteria, fungus and cancer cell lines.

Publisher

Asian Journal of Chemistry

Subject

General Chemistry

Reference28 articles.

1. The chemistry of isatins: a review from 1975 to 1999

2. G. Chen, X.J. Hao, Q.Y. Sun and J. Ding, Chem. Pap., 64, 673 (2010).

3. Synthesis and Antitumor Activity Evaluation of Regioselective Spiro [pyrrolidine-2,3'-oxindole] Compounds

4. Spiro[pyrrolidine-2,3′-oxindole] derivatives synthesized by novel regionselective 1,3-dipolar cycloadditions

5. Michael Addition between Isatin and Acrylate Derivatives

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. New Strategies in the Chemical Control of Fusarium Oxysporum using Synthetic Bioisosteres of Secondary Metabolites: A Review of the Synthetic Methods for Novel Compounds with Potential Antifungal Activity;Mini-Reviews in Organic Chemistry;2023-05-16

2. The Antibacterial Activity of Isatin Hybrids;Current Topics in Medicinal Chemistry;2022-01

3. Theoretical Molecular Properties Prediction, Docking and Antimicrobial Studies on Anisidine-Isatin Schiff Bases;Asian Journal of Chemistry;2021