Survival and grade of the glioma prediction using transfer learning

Author:

Valbuena Rubio Santiago1,García-Ordás María Teresa2,García-Olalla Olivera Oscar1,Alaiz-Moretón Héctor2,González-Alonso Maria-Inmaculada3,Benítez-Andrades José Alberto4ORCID

Affiliation:

1. IA Department, Xeridia S.L., León, León, Spain

2. SECOMUCI Research Group, Escuela de Ingenierías Industrial e Informática, Universidad de León, León, Spain

3. Department of Electric, Systems and Automatics Engineering, Universidad de León, León, Spain

4. SALBIS Research Group, Department of Electric, Systems and Automatics Engineering, Universidad de León, León, Spain

Abstract

Glioblastoma is a highly malignant brain tumor with a life expectancy of only 3–6 months without treatment. Detecting and predicting its survival and grade accurately are crucial. This study introduces a novel approach using transfer learning techniques. Various pre-trained networks, including EfficientNet, ResNet, VGG16, and Inception, were tested through exhaustive optimization to identify the most suitable architecture. Transfer learning was applied to fine-tune these models on a glioblastoma image dataset, aiming to achieve two objectives: survival and tumor grade prediction.The experimental results show 65% accuracy in survival prediction, classifying patients into short, medium, or long survival categories. Additionally, the prediction of tumor grade achieved an accuracy of 97%, accurately differentiating low-grade gliomas (LGG) and high-grade gliomas (HGG). The success of the approach is attributed to the effectiveness of transfer learning, surpassing the current state-of-the-art methods. In conclusion, this study presents a promising method for predicting the survival and grade of glioblastoma. Transfer learning demonstrates its potential in enhancing prediction models, particularly in scenarios with limited large datasets. These findings hold promise for improving diagnostic and treatment approaches for glioblastoma patients.

Publisher

PeerJ

Subject

General Computer Science

Reference55 articles.

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