Arundo donax L.: An overview on its traditional and ethnomedicinal importance, phytochemistry, and pharmacological aspects

Abstract

Arundo donax L. (Giant reed) is a grass species belong to Poaceae family with a myriad of uses such as traditional and ethnomedicinal values, bioenergy, and socio-economic importance. The plant is used in conventional medicine to treat various disorders related to skin, gastrointestinal, skeletal, menstrual problems, respiratory and urinary diseases. The present review summarises the scattered information on socio-economic importance, ethnomedicinal uses, phytochemistry and pharmacological aspects of this plant. We conducted a rigorous literature survey using databases such as Scopus, Science Direct, Web of Science, Google Scholar, and PubMed entering keywords like A. donax, Giant reed, and Spanish reed, etc. Phytochemical investigations have identified several alkaloids, terpenoids, sterols, phenolics, and lignin derivatives. The isolated phytoconstituents are reported to exhibit multiple pharmacological activities such as anti-bacterial, anti-oxidant, anti-proliferative, anti-spasmolytic, and also used to treat helminthic infestations in cattle. However, the scientific validity of traditional practices to cure various diseases has not been correctly evaluated yet. Therefore, it is recommended to further investigate the plant for clinical trials to unleash its therapeutic importance towards chemical characterisation for drug discovery and development in the pharmacological field.