Carcinogenic effects of polychlorinated biphenyls

Author:

Faroon Obaid M1,Keith Sam2,Jones Dennis2,De Rosa Christopher2

Affiliation:

1. Agency for Toxic Substances and Disease Registry (ATSDR), US Department of Health and Human Services, Atlanta, Georgia 30333, USA,

2. Agency for Toxic Substances and Disease Registry (ATSDR), US Department of Health and Human Services, Atlanta, Georgia 30333, USA

Abstract

As part of its mandate, the Agency for Toxic Substances and Disease Registry (ATSDR) prepares toxicological profiles on hazardous chemicals found at Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) National Priorities List (NPL) sites that have the greatest public health impact. These profiles comprehensively summarize toxicological and environmental information. This article constitutes the release of an important section of the Toxicological profile for polychlorinated biphenyls [ATSDR. 2000: Toxicological profile for polychlorinated biphenyls. Atlanta, GA: US Department of Health and Human Services, Agency for Toxic Substances and Disease Registry.] into the scientific literature. This article focuses on the carcinogenic effects of this group of synthetic organic chemicals (polychlorinated biphenyls) in humans and animals. Information on other health effects, toxicokinetics, mechanisms of toxicity, biomarkers, interactions, chemical and physical properties, potential for human exposure, and regulations and advisories is detailed in the profile.

Publisher

SAGE Publications

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health,Toxicology

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