The protective effect of hydrated sodium calcium aluminosilicate against the adverse effects of Aflatoxin B1 on D. melanogaster

Author:

Şişman Turgay1

Affiliation:

1. Department of Biology, Science and Art Faculty, Atatürk University, 25240 Erzurum, Turkey,

Abstract

The main aim of this study was to investigate the effects of Aflatoxin B1(AFB1) and Aflatoxin B1-hydrated sodium calcium aluminosilicate (HSCAS) on various developmental stages of Drosophila melanogaster. Different concentrations of AFB1and HSCAS-AFB1were administered during the developmental periods of the fly (egg, larvae and pupae). When the F1progeny of control and application groups were compared, AFB1was found to extend the process of metamorphosis and decrease the total number of offspring. However, these negative effects were inhibited with HSCAS treatment at different concentrations (5.0 and 10.0 ppm). These results suggest that HSCAS could effectively inhibit AFB1-induced abnormalities in the developmental stages of D. melanogaster.

Publisher

SAGE Publications

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health,Toxicology

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