Flk1-GFP BAC Tg Mice: An Animal Model for the Study of Blood Vessel Development

Author:

ISHITOBI Hiroyuki1,MATSUMOTO Ken1,AZAMI Takuya1,ITOH Fumiko2,ITOH Susumu23,TAKAHASHI Satoru1,EMA Masatsugu1

Affiliation:

1. Department of Anatomy and Embryology, Institute of Basic Medical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba

2. Department of Experimental Pathology, Graduate School of Comprehensive Human Sciences, University of Tsukuba

3. High Technology Research Center, Showa Pharmaceutical University Laboratory of Biochemistry, Showa Pharmaceutical University

Publisher

Japanese Association for Laboratory Animal Science

Subject

General Veterinary,General Biochemistry, Genetics and Molecular Biology,Animal Science and Zoology,General Medicine

Reference19 articles.

1. 1. Downs, K.M. and Davies, T. 1993. Staging of gastrulating mouse embryos by morphological landmarks in the dissecting microscope. Development 118: 1255–1266.

2. Combinatorial effects ofFlk1andTal1on vascular and hematopoietic development in the mouse

3. 3. Ema, M., Takahashi, S., and Rossant, J. 2006. Deletion of the selection cassette, but not cis-acting elements, in taegeted Flk1-lacZ allele reveals Flk1 expression in multipotent mesodermal projenitors. Blood 107: 111–117.

4. 4. Ema, M., Yokomizo, T., Wakamatsu, A., Terunuma, T., Yamamoto, M., and Takahashi, S. 2006. Primitive erythropoiesis from mesodermal precursors expressing VE-cadherin, PECAM-1, Tie2, endoglin, and CD34 in the mouse embryo. Blood 108: 4018–4024.

5. Vascular Endothelial Growth Factor: Basic Science and Clinical Progress

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