Staging of gastrulating mouse embryos by morphological landmarks in the dissecting microscope

Author:

Downs K.M.1,Davies T.1

Affiliation:

1. Department of Zoology, University of Oxford, UK.

Abstract

We describe and illustrate a set of morphological landmarks for classifying mouse embryos by gross morphology from before gastrulation to the beginning of organogenesis. These landmarks are visible at the resolution of the dissecting microscope in embryos that are intact except for reflexion of Reichert's membrane. Adoption of these criteria should facilitate interpretation of both the expression patterns of genes and the consequences of experimental manipulation of embryos during early postimplantation development.

Publisher

The Company of Biologists

Subject

Developmental Biology,Molecular Biology

Reference19 articles.

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4. Relationship between rate at embryonic developemnt and the preponderance of cranial neural tube defects in females.;Brook;Genet. Res,1991

5. A Y-chromosomal effect on blastocyst cell number in mice.;Burgoyne;Development,1993

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