IS OBESITY ASSOCIATED WITH PROGRESSION OF STEROID-RESISTANT NEPHROTIC SYNDROME IN CHILDREN?

Abstract

THE AIM:to study potential associations of obesity with progression of idiopathic steroid-resistant nephrotic syndrome (SRNS) in children.PATIENTS AND METHODS.We performed a retrospective one-center 15-years follow up study of SRNS course in 65 children divided into 2 groups: 1) with obesity (n=48); 2) with normal weight or overweight (n=17).RESULTS.In patients with SRNS and obesity we found no associations with clinical predictors of unfavorable outcome – arterial hypertension and proteinuria and also with glomerular filtration rate at recent hospitalization. Renal survival was comparable between SRNS patients with obesity and normal weight or overweight.CONCLUSION. Obesity does not have any impact on course and prognosis of SRNS in children and can not be considered as risk factor for the disease progression.