Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascade Inhibitors: How Mutations Can Result in Therapy Resistance and How to Overcome Resistance-Reference-Cited by-同舟云学术

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascade Inhibitors: How Mutations Can Result in Therapy Resistance and How to Overcome Resistance

Published:2012-10-20 Issue:10 Volume:3 Page:1068-1111
ISSN:1949-2553
Container-title:Oncotarget
language:en
Short-container-title:Oncotarget

Author:

McCubrey James A.¹,Steelman Linda S.¹,Chappell William H.¹,Abrams Stephen L.¹,Franklin Richard A.¹,Montalto Giuseppe²,Cervello Melchiorre³,Libra Massimo⁴,Candido Saverio⁴,Malaponte Grazia⁴,Mazzarino Maria C.⁴,Fagone Paolo⁴,Nicoletti Ferdinando⁴,Bäsecke Jörg⁵,Mijatovic Sanja⁶,Maksimovic-Ivanic Danijela⁶,Milella Michele⁷,Tafuri Agostino⁸,Chiarini Francesca⁹,Evangelisti Camilla⁹,Cocco Lucio¹⁰,Martelli Alberto M.⁹¹⁰

Affiliation:

1. Department of Microbiology and Immunology, Brody School of Medicine at East Carolina University, Greenville, NC, USA

2. Department of Internal Medicine and Specialties, University of Palermo, Palermo, Italy

3. Consiglio Nazionale delle Ricerche, Istituto di Biomedicina e Immunologia Molecolare “Alberto Monroy”, Palermo, Italy

4. Department of Bio-Medical Sciences, University of Catania, Catania, Italy

5. Department of Medicine, University of Göttingen, Göttingen, Germany

6. Department of Immunology, Instititue for Biological Research “Sinisa Stankovic”, University of Belgrade, Belgrade, Serbia

7. Regina Elena National Cancer Institute, Rome, Italy

8. Sapienza, University of Rome, Department of Cellular Biotechnology and Hematology, Rome, Italy

9. Institute of Molecular Genetics, National Research Council-Rizzoli Orthopedic Institute, Bologna, Italy

10. Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy

Publisher

Impact Journals, LLC

Subject

Oncology

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