Inhibition of ALK1 signaling with dalantercept combined with VEGFR TKI leads to tumor stasis in renal cell carcinoma

Author:

Wang Xiaoen1,Solban Nicolas2,Khanna Prateek3,Callea Marcella4,Song Jiaxi4,Alsop David C.1,Pearsall R. Scott2,Atkins Michael B.5,Mier James W.3,Signoretti Sabina4,Alimzhanov Marat2,Kumar Ravi2,Bhasin Manoj K.6,Bhatt Rupal S.3

Affiliation:

1. Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA

2. Acceleron Pharma, Inc., Cambridge, MA, USA

3. Division of Hematology-Oncology and Cancer Biology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA

4. Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA

5. Departments of Oncology and Medicine, Georgetown Lombardi Comprehensive Cancer Center, Washington, DC, USA

6. Division of Interdisciplinary Medicine & Biotechnology, and Genomics, Proteomics, Bioinformatics and Systems Biology Center, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA

Publisher

Impact Journals, LLC

Subject

Oncology

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