Structural basis of nSH2 regulation and lipid binding in PI3Kα

Author:

Miller Michelle S.12,Schmidt-Kittler Oleg345,Bolduc David M.67,Brower Evan T.38,Chaves-Moreira Daniele9,Allaire Marc10,Kinzler Kenneth W.3,Jennings Ian G.1,Thompson Philip E.,Cole Philip A.6,Amzel L. Mario9,Vogelstein Bert3,Gabelli Sandra B.91112

Affiliation:

1. Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Parkville, Victoria, Australia

2. Present Address: Department of Oncology, Johns Hopkins University School of Medicine, Baltimore Maryland, USA

3. Ludwig Center for Cancer Genetics and Therapeutics and Howard Hughes Medical Institutions, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

4. Present Address: Sanofi, Cambridge, Massachusetts

5. Present Address: Berkeley Center for Structural Biology, Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California

6. Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

7. Present Address: Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts

8. Present Address: Paragon Bioservices, Baltimore, Maryland

9. Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

10. Photon Sciences, Brookhaven National Laboratory, Upton, New York, USA

11. Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

12. Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

Publisher

Impact Journals, LLC

Subject

Oncology

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