Molecular basis for Gβγ-mediated activation of phosphoinositide 3-kinase γ
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Publisher
Springer Science and Business Media LLC
Link
https://www.nature.com/articles/s41594-024-01265-y.pdf
Reference46 articles.
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3. Stephens, L. R., Hughes, K. T. & Irvine, R. F. Pathway of phosphatidylinositol(3,4,5)-trisphosphate synthesis in activated neutrophils. Nature 351, 33–39 (1991).
4. Cash, J. N. et al. Cryo-electron microscopy structure and analysis of the P-Rex1-Gβγ signaling scaffold. Sci. Adv. 5, eaax8855 (2019).
5. Vanhaesebroeck, B., Perry, M. W. D., Brown, J. R., André, F. & Okkenhaug, K. PI3K inhibitors are finally coming of age. Nat. Rev. Drug Discov. 20, 741–769 (2021).
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