Automated tracking of tumor-stroma morphology in microtissues identifies functional targets within the tumor microenvironment for therapeutic intervention

Author:

Åkerfelt Malin12,Bayramoglu Neslihan3,Robinson Sean4567,Toriseva Mervi128,Schukov Hannu-Pekka8,Härmä Ville2,Virtanen Johannes2,Sormunen Raija9,Kaakinen Mika10,Kannala Juho3,Eklund Lauri10,Heikkilä Janne3,Nees Matthias12

Affiliation:

1. Turku Centre for Biotechnology, University of Turku, Turku, FI-20520, Finland

2. VTT Technical Research Centre of Finland, Turku, FI-20521, Finland

3. Centre for Machine Vision Research, University of Oulu, Oulu, FI-90014, Finland

4. Department of Mathematics and Statistics, University of Turku, Turku, FI-20014, Finland

5. University Grenoble Alpes, iRTSV-BGE, Grenoble, F-38000, France

6. CEA, iRTSV-BGE, Grenoble, F-38000, France

7. INSERM, BGE, Grenoble, F-38000, France

8. Institute of Biomedicine, University of Turku, Turku, FI-20520, Finland

9. Biocenter Oulu and Department of Pathology, University of Oulu and Oulu University Hospital, Oulu, FI-90220, Finland

10. Oulu Center for Cell-Matrix Research, Biocenter Oulu and Faculty of Biochemistry and Molecular Medicine, University of Oulu, Oulu, FI-90014, Finland

Publisher

Impact Journals, LLC

Subject

Oncology

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