ERα propelled aberrant global DNA hypermethylation by activating the DNMT1 gene to enhance anticancer drug resistance in human breast cancer cells

Author:

Si Xinxin12,Liu Yue12,Lv Jinghuan3,Ding Haijian12,Zhang Xin A.4,Shao Lipei12,Yang Nan1,Cheng He12,Sun Luan12,Zhu Dongliang2,Yang Yin12,Li Andi12,Han Xiao1,Sun Yujie1562

Affiliation:

1. Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, Nanjing, Jiangsu, China

2. Department of Cell Biology, Nanjing Medical University, Nanjing, Jiangsu, China

3. Department of Pathology, Municipal Hospital, Suzhou Hospital Affiliated to Nanjing Medical University, Suzhou, Jiangsu, China

4. Department of Physiology and Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA

5. Collaborative Innovation Center for Cancer Medicine, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Nanjing Medical University, Nanjing, Jiangsu, China

6. State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, Jiangsu, China

Publisher

Impact Journals, LLC

Subject

Oncology

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