Author:
Hoff Andrew M.,Connolly Richard,Chapman Taryn,Llewellyn J.,Gilbert Richard,Ugen Kenneth,Jaroszeski Mark
Abstract
We report the design, development and characterization of new atmospheric plasma-based protocols currently being examined in vivo using small animal models. Previously developed electric field mediated drug and gene delivery protocols use a pulsed DC voltage applied between electrodes on or in tissue to generate the required electric field to induce delivery of molecules. Plasma sources deliver roughly a million times less charge to skin compared with direct electrode-driven delivery methods, yet the efficiency of the process is dramatically similar with respect to the introduction of molecules to skin cells.
Publisher
The Electrochemical Society
Cited by
1 articles.
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