Tweaking the Performance of Dielectric Modulated Junctionless Double Gate Metal Oxide Field Effect Transistor-Based Label-Free Biosensor

Abstract

In this study, we have explored the characteristics of a dielectric-modulated, junctionless (JL) double gate (DG) metal oxide field-effect transistor (MOSFET) featuring a misaligned cavity. Our investigation primarily revolves around proposing optimized device dimensions by examining the influence of varying the height and length of the cavity on the device’s sensitivity. We have delved into the variation of sensitivity parameters, including threshold voltage, ON current, ON-OFF current ratio, and transconductance. Furthermore, our research delves into the effects of both charged and neutral biomolecules on the DC characteristics of the proposed biosensor. We have scrutinized the placement and fill-factor variations of biomolecules within the cavity region, elucidating their impact on sensitivity. Notably, we observed that a 100% filled cavity yields the highest sensitivity. Additionally, this work encompasses a comprehensive exploration of the practical biosensing mechanism tailored for detecting Streptavidin. Based on the ON-OFF current ratio, a maximum selectivity factor of 2.38 (biotarget over bioreceptor) has been observed. Our extensive simulations, conducted using SILVACO ATLAS, rigorously investigate the effects we describe. Altogether, this study highlights the potential of misaligned-cavity JL-DG-MOSFET-based label-free biosensors as cost-effective and simplified analytical tools for biomolecule detection.