Abstract
Here, we have developed a sensitive electrochemical sensor for famotidine (FAT) using Cu2O nanoparticles and reduced graphene oxide (rGO). The Cu2O nanoparticles and rGO were synthesized through a simple process and characterized by versatile analytical techniques. The prepared Cu2O nanoparticles and rGO were taken to modify the carbon paste electrode (Cu2O/rGO/CPE) and applied for the electrochemical analysis of the FAT at pH 6.0. Cu2O/rGO/CPE showed superior response to determine FAT, attributed to the high surface area of rGO and the electrocatalytic properties of Cu2O nanoparticles. The designed FAT sensor exhibited two dynamic linear ranges from 0.1–3.0 μM and 3.0–50.0 μM with a limit of detection of 0.08 μM (S/N = 3) using a differential pulse voltammetry. The proposed sensor also showed a repeatable and stable response over one month with negligible interference from usual organic and inorganic species. The sensor was also validated to measure FAT in real samples (urine, serum and pharmaceutical tablet) with good recoveries from 99.6 to 110.9%.
Publisher
The Electrochemical Society
Subject
Materials Chemistry,Electrochemistry,Surfaces, Coatings and Films,Condensed Matter Physics,Renewable Energy, Sustainability and the Environment,Electronic, Optical and Magnetic Materials
Cited by
4 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献