Local expression of IGF‐1 accelerates muscle regeneration by rapidly modulating inflammatory cytokines and chemokines

Author:

Pelosi Laura1,Giacinti Cristina1,Nardis Chiara1,Borsellino Giovanna2,Rizzuto Emanuele1,Nicoletti Carmine1,Wannenes Francesca3,Battistini Luca2,Rosenthal Nadia45,Molinaro Mario1,Musar Antoniò16

Affiliation:

1. Department of Histology and Medical EmbryologyCE-BEMM and Interuniversity Institute of MyologyUniversity of Rome “La Sapienza”RomeItaly

2. Neuroimmunology UnitSanta Lucia Foundation Scientific InstituteRomeItaly

3. IRCCS San RaffaeleRomeItaly

4. EMBL Mouse Biology ProgramMonterotondoItaly

5. Harefield Heart Science CentreNational Heart and Lung InstituteImperial College LondonLondonUK

6. Edith Cowan UniversityPerthWestern AustraliaAustralia

Funder

Fondazione Telethon

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Reference35 articles.

1. Inflammatory cell response to acute muscle injury;Tidball J. G.;Med. Sci. Sports. Exerc.,1995

2. Muscle injuries and repair: current trends in research;Huard J.;J. Bone Joint Surg. Am.,2002

3. Muscle injuries: biology and treatment;Jarvinen T. A.;Am. J. Sports Med.,2005

4. Macrophages regulate proliferation and differentiation of satellite cells;Cantini M.;Biochem. Biophys. Res. Commun.,1994

5. Macrophage-released factor stimulates selectively myogenic cells in primary muscle culture;Cantini M.;J. Neuropathol. Exp. Neurol.,1995

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