Controlling distinct signaling states in cultured cancer cells provides a new platform for drug discovery

Author:

Poser Steven W.1,Otto Oliver2,Arps‐Forker Carina1,Ge Yan23,Herbig Maik2,Andree Cordula4,Gruetzmann Konrad567,Adasme Melissa F.2,Stodolak Szymon8,Nikolakopoulou Polyxeni1,Park Deric M.910,Mcintyre Alan8,Lesche Mathias211,Dahl Andreas211,Lennig Petra12,Bornstein Stefan R.110,Schroeck Evelin1356,Klink Barbara1356,Leker Ronen R.14,Bickle Marc4,Chrousos George P.1516,Schroeder Michael2,Cannistraci Carlo Vittorio317,Guck Jochen2,Androutsellis‐Theotokis Andreas181011

Affiliation:

1. Department of Internal Medicine III Technische Universität Dresden Dresden Germany

2. Biotechnology Center (BIOTEC) Technische Universität Dresden Dresden Germany

3. Biomedical Cybernetics Group Department of Physics Biotechnology Center (BIOTEC) Center for Molecular and Cellular Bioengineering (CMCB) Center for Systems Biology Dresden (CSBD) Technische Universität Dresden Dresden Germany

4. Technology Development Studio Max Planck Institute of Molecular Cell Biology and Genetics Dresden Germany

5. Core Unit for Molecular Tumor Diagnostics (CMTD) National Center for Tumor Diseases (NCT) Dresden Dresden Germany

6. German Cancer Consortium (DKTK) Dresden Germany

7. German Cancer Research Center (DKFZ) Heidelberg Germany

8. Division of Cancer and Stem Cells University of Nottingham Nottingham United Kingdom

9. Department of Neurology Committee on Clinical Pharmacology and Pharmacogenomics The University of Chicago Chicago Illinois USA

10. Innate Repair London United Kingdom

11. Center for Regenerative Therapies Dresden Dresden Germany

12. B CUBE ‐ Center for Molecular Bioengineering Technische Universität Dresden Dresden Germany

13. Institute for Clinical Genetics Faculty of Medicine Carl Gustav Cams Technische Universität Dresden Dresden Germany

14. Stroke Unit Department of Neurology Stroke Center Peritz and Chantal Sheinberg Cerebrovascular Research Laboratory Hadassah‐Hebrew University Medical Center Jerusalem Israel

15. First Department of Pediatrics National and Kapodistrian University Athens Medical School Athens Greece

16. Aghia Sophia Children's Hospital Athens Greece

17. Brain Bio‐Inspired Computing (BBC) Lab IRCCS Centra Neurolesi Bonino Pulejo Messina Italy

Funder

Deutsche Forschungsgemeinschaft

Alexander von Humboldt-Stiftung

Sächsisches Staatsministerium für Wissenschaft und Kunst

Technische Universität Dresden

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

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