The immune modulatory peptide FhHDM‐1 secreted by the helminth Fasciola hepatica prevents NLRP3 inflammasome activation by inhibiting endolysosomal acidification in macrophages-Reference-Cited by-同舟云学术

The immune modulatory peptide FhHDM‐1 secreted by the helminth Fasciola hepatica prevents NLRP3 inflammasome activation by inhibiting endolysosomal acidification in macrophages

Published:2016-09-28 Issue:1 Volume:31 Page:85-95
ISSN:0892-6638
Container-title:The FASEB Journal
language:en
Short-container-title:FASEB j.

Author:

Alvarado Raquel¹,To Joyce¹,Lund Maria E.¹,Pinar Anita²,Mansell Ashley²,Robinson Mark W.³,O'Brien Bronwyn A.¹,Dalton John P.³,Donnelly Sheila¹

Affiliation:

1. School of Life SciencesUniversity of Technology Sydney Sydney New South Wales Australia

2. Monash Institute of Medical ResearchMonash University Clayton Victoria Australia

3. School of Biological SciencesQueen's University Belfast Northern Ireland

Funder

Diabetes Australia Research Trust

National Health and Medical Research Council

H2020 European Research Council

Biotechnology and Biological Sciences Research Council

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.201500093r

Reference53 articles.

1. Accelerated Intestinal Epithelial Cell Turnover: A New Mechanism of Parasite Expulsion

2. IL‐1β suppresses innate IL‐25 and IL‐33 production and maintains helminth chronicity;Zaiss M. M.;PLoS Pathog,2013

3. IL-33, an Interleukin-1-like Cytokine that Signals via the IL-1 Receptor-Related Protein ST2 and Induces T Helper Type 2-Associated Cytokines

4. IL-25 Induces IL-4, IL-5, and IL-13 and Th2-Associated Pathologies In Vivo

5. Fasciola hepatica vaccine: We may not be there yet but we’re on the right road

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