The pseudoprotease iRhom1 controls ectodomain shedding of membrane proteins in the nervous system

Author:

Tüshaus Johanna12,Müller Stephan A.12,Shrouder Joshua3,Arends Martina14,Simons Mikael145,Plesnila Nikolaus35,Blobel Carl P.678,Lichtenthaler Stefan F.125

Affiliation:

1. German Center for Neurodegenerative Diseases (DZNE) Munich Germany

2. Neuroproteomics School of Medicine Klinikum rechts der Isar Technical University of Munich Munich Germany

3. Institute for Stroke and Dementia Research (ISD) Klinikum der Universität MünchenLudwig‐Maximilians‐University Munich Munich Germany

4. Institute of Neuronal Cell Biology Technical University Munich Munich Germany

5. Munich Cluster for Systems Neurology (SyNergy) Munich Germany

6. Department of Physiology, Biophysics and Systems Biology Weill Cornell Medicine New York New York USA

7. Department of Medicine Weill Cornell Medicine New York New York USA

8. Arthritis and Tissue Degeneration Program Hospital for Special Surgery New York New York USA

Funder

Deutsche Forschungsgemeinschaft

Bundesministerium für Bildung und Forschung

National Institutes of Health

Boehringer Ingelheim Fonds

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

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