Mechanical stretch activates piezo1 in caveolae of alveolar type I cells to trigger ATP release and paracrine stimulation of surfactant secretion from alveolar type II cells
Author:
Affiliation:
1. Institute of General Physiology Ulm University Ulm Germany
2. Institute of Analytical and Bioanalytical Chemistry Ulm University Ulm Germany
3. Institute of Molecular and Cellular Anatomy Ulm University Ulm Germany
Funder
Deutsche Forschungsgemeinschaft
Publisher
Wiley
Subject
Genetics,Molecular Biology,Biochemistry,Biotechnology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.202000613RRR
Reference90 articles.
1. Pulmonary Surfactant Pathophysiology: Current Models and Open Questions
2. Mechanisms of surfactant exocytosis in alveolar type II cells in vitro and in vivo;Dietl P;News Physiol Sci,2001
3. Spatio-temporal aspects, pathways and actions of Ca2+ in surfactant secreting pulmonary alveolar type II pneumocytes
4. Secretion in Alveolar Type II Cells at the Interface of Constitutive and Regulated Exocytosis
5. Threshold calcium levels for lamellar body exocytosis in type II pneumocytes
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