Interleukin‐11 (IL‐11) receptor cleavage by the rhomboid protease RHBDL2 induces IL‐11 trans‐signaling-Reference-Cited by-同舟云学术

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Interleukin‐11 (IL‐11) receptor cleavage by the rhomboid protease RHBDL2 induces IL‐11 trans‐signaling

Published:2021-02-10 Issue:3 Volume:35 Page:
ISSN:0892-6638
Container-title:The FASEB Journal
language:en
Short-container-title:FASEB j.

Author:

Koch Lydia¹,Kespohl Birte²,Agthe Maria¹,Schumertl Tim²,Düsterhöft Stefan³,Lemberg Marius K.⁴,Lokau Juliane²,Garbers Christoph²^ORCID

Affiliation:

1. Institute of Biochemistry Kiel University Kiel Germany

2. Department of Pathology, Medical Faculty Otto‐von‐Guericke‐University Magdeburg Magdeburg Germany

3. Institute of Molecular Pharmacology RWTH Aachen University Aachen Germany

4. Center for Molecular Biology of Heidelberg University (ZMBH) DKFZ‐ZMBH Alliance Heidelberg Germany

Funder

Deutsche Forschungsgemeinschaft

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.202002087R

Reference55 articles.

1. Interleukin-6 and interleukin-11: same same but different

2. More than a sidekick: the IL-6 family cytokine IL-11 links inflammation to cancer

3. Plasticity and cross-talk of Interleukin 6-type cytokines

4. IL-11 signaling as a therapeutic target for cancer

5. Regulation of interleukin-11 protein and mRNA expression in neonatal and adult fibroblasts and endothelial cells

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1. Extensive targeting of chemical space at the prime side of ketoamide inhibitors of rhomboid proteases by branched substituents empowers their selectivity and potency;European Journal of Medicinal Chemistry;2024-09

2. MicroRNAs and proteolytic cleavage of receptors in cancers: A comprehensive review of regulatory interactions and therapeutic implications;Heliyon;2024-04

3. Cytokines of the interleukin-6 family as emerging targets in inflammatory bowel disease;Expert Opinion on Therapeutic Targets;2024-01-23

4. Extensive Targeting of Chemical Space at the Prime Side of Ketoamide Inhibitors of Rhomboid Proteases by Branched Substituents Empowers Their Selectivity and Potency;2024

5. Molecular characterization of the craniosynostosis‐associated interleukin‐11 receptor variants p.T306_S308dup and p.E364_V368del;The FEBS Journal;2023-12-07

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