Blood‐brain barrier transport using a high affinity, brain‐selective VNAR antibody targeting transferrin receptor 1-Reference-Cited by-同舟云学术

Blood‐brain barrier transport using a high affinity, brain‐selective VNAR antibody targeting transferrin receptor 1

Published:2020-11-25 Issue:2 Volume:35 Page:
ISSN:0892-6638
Container-title:The FASEB Journal
language:en
Short-container-title:FASEB j.

Author:

Stocki Pawel¹²,Szary Jaroslaw¹²,Rasmussen Charlotte L. M.³,Demydchuk Mykhaylo¹²,Northall Leandra¹²,Logan Diana Bahu¹²,Gauhar Aziz¹²,Thei Laura¹²,Moos Torben³,Walsh Frank S.¹²,Rutkowski J. Lynn¹²

Affiliation:

1. Ossianix, Inc Stevenage Bioscience Catalyst Stevenage UK

2. Ossianix, Inc Philadelphia PA USA

3. Laboratory of Neurobiology Department of Health Science and Technology Aalborg University Aalborg Denmark

Funder

Lundbeckfonden

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.202001787R

Reference52 articles.

1. Transferrin and transferrin receptors update

2. Anti-transferrin receptor antibody and antibody-drug conjugates cross the blood-brain barrier.

3. Targeting the transferrin receptor for brain drug delivery

4. Addressing Safety Liabilities of TfR Bispecific Antibodies That Cross the Blood-Brain Barrier

5. Blood-Brain Barrier Transport, Plasma Pharmacokinetics, and Neuropathology Following Chronic Treatment of the Rhesus Monkey with a Brain Penetrating Humanized Monoclonal Antibody Against the Human Transferrin Receptor

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